报告题目：明星、基因与抉择

报 告 人：张锋 教授（复旦大学）
报告时间：2020年10月19日14:00-16:00

报告地点：云南大学呈贡校区力行楼1301

个人简介

张锋，复旦大学附属妇产科医院教授、遗传工程国家重点实验室副主任。获教育部“长江学者”特聘教授、国家杰出青年科学基金、国家万人计划科技创新领军人才等计划支持。兼任中国遗传学会青年委员会主任委员、中国优生科学协会常务理事。获第十五届中国青年科技奖、2017年度教育部自然科学奖一等奖、药明康德生命化学杰出成就奖。致力于人类遗传变异导致不孕不育、出生缺陷等疾病的基础和转化研究。已在New England Journal of Medicine, Nature Genetics, American Journal of Human Genetics,Cell Research, Science Advances等SCI期刊发表论著130篇。

代表性论文

1. Wang L#, Zhang Y#, Fu X#, Dong S#, Tang S, Zhang N, Song C, Yang N, Zhang L, Wang H, Shi H, Jin L,Zhang F*, Li J#, Hua K*. Joint utilization of genetic analysis and semi-cloning technology reveals a digenic etiology of Müllerian anomalies. Cell Research, 2020, 30(1): 91-94.

2. Liu C, He X, Liu W, Yang S, Wang L, Li W, Wu H, Tang S, Ni X, Wang J, Gao Y, Tian S, Zhang L, Cong J, Zhang Z, Tan Q, Zhang J, Li H, Zhong Y, Lv M, Li J, Jin L, Cao Y*,Zhang F*. Bi-allelic Mutations in TTC29 Cause Male Subfertility with Asthenoteratospermia in Humans and Mice. American Journal of Human Genetics, 2019, 105: 1168-1181.

3. Liu W#, He X#, Yang S#, Zouari R, Wang J, Wu H, Kherraf ZE, Liu C, Coutton C, Zhao R, Tang D, Tang S, Lv M, Fang Y, Li W, Li H, Zhao J, Wang X, Zhao S, Zhang J, Arnoult C, Jin L, Zhang Z, Ray PF, Cao Y*,Zhang F*. Bi-allelic Mutations in TTC21A Induce Asthenoteratospermia in Humans and Mice. American Journal of Human Genetics, 2019, 104(4): 738-748.

4. Tang S#, Wang X#, Li W#, Yang X#, Li Z#, Liu W, Li C, Zhu Z, Wang L, Wang J, Zhang L, Sun X, Zhi E, Wang H, Li H, Jin L, Luo Y, Wang J, Yang S*,Zhang F*. Biallelic Mutations in CFAP43 and CFAP44 Cause Male Infertility with Multiple Morphological Abnormalities of the Sperm Flagella. American Journal of Human Genetics, 2017, 100(6): 854-864.

5. Wu N#, Ming X#, Xiao J#, Wu Z#, Chen X#, Shinawi M, Shen Y, Yu G, Liu J, Xie H, Gucev ZS, Liu S, Yang N, Al-Kateb H, Chen J, Zhang J, Hauser N, Zhang T, Tasic V, Liu P, Su X, Pan X, Liu C, Wang L, Shen J, Shen J, Chen Y, Zhang T, Zhang J, Choy KW, Wang J, Wang Q, Li S, Zhou W, Guo J, Wang Y, Zhang C, Zhao H, An Y, Zhao Y, Wang J, Liu Z, Zuo Y, Tian Y, Weng X, Sutton VR, Wang H, Ming Y, Kulkarni S, Zhong TP, Giampietro PF, Dunwoodie SL, Cheung SW, Zhang X, Jin L, Lupski JR, Qiu G*,Zhang F*. TBX6 Null Variants and a Common Hypomorphic Allele in Congenital Scoliosis. New England Journal of Medicine, 2015, 372: 341-350.